China (Mainland)
Baricitinib CAS NO.1187594-09-7
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- Product Details
Keywords
- Baricitinib
- INCB 028050; LY 3009104; INCB028050; LY3009104; LY-3009104; INCB-028050
- 1187594-09-7
Quick Details
- ProName: Baricitinib
- CasNo: 1187594-09-7
- Molecular Formula: C16H17N7O2S
- PackAge: 10mg;50mg;100mg
- ProductionCapacity: 50-100 Metric Ton/Day
- Purity: 98% min
- Storage: -20℃
- LimitNum: 0 Metric Ton
Superiority
Baricitinib(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.
IC50 Value: JAK1 (5.9 nM) and JAK2 (5.7 nM) [1].
Target: JAK1/2
in vitro: INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL-6 and IL-23 at concentrations <50 nM. Significant efficacy
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Details
Baricitinib(INCB 028050; LY 3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.
IC50 Value: JAK1 (5.9 nM) and JAK2 (5.7 nM) [1].
Target: JAK1/2
in vitro: INCB028050 inhibits intracellular signaling of multiple proinflammatory cytokines including IL-6 and IL-23 at concentrations <50 nM. Significant efficacy
url：#
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