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Home > Products >  (-)-JQ-1

(-)-JQ-1 CAS NO.1268524-71-5

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  • Product Details

Keywords

  • (-)-JQ-1
  • JQ-1; JQ1
  • 1268524-71-5

Quick Details

  • ProName: (-)-JQ-1
  • CasNo: 1268524-71-5
  • Molecular Formula: C23H25ClN4O2S
  • PackAge: 5mg;10mg;50mg;
  • ProductionCapacity: 50-100 Metric Ton/Day
  • Purity: 98% min
  • Storage: -20℃
  • LimitNum: 0 Metric Ton

Superiority

(-)-JQ-1,  the stereoisomer (+)-JQ1,  showed no significant interaction with any bromodomain; (+)-JQ1 is an inhibitor for the BET.
IC50 value:
Target: BET bromodomain
The ()-JQ1 stereoisomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.

 

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Details

(-)-JQ-1,  the stereoisomer (+)-JQ1,  showed no significant interaction with any bromodomain; (+)-JQ1 is an inhibitor for the BET.
IC50 value:
Target: BET bromodomain
The ()-JQ1 stereoisomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.

 

url：#

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