China (Mainland)
Vemurafenib CAS NO.918504-65-1
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- Product Details
Keywords
- Vemurafenib
- PLX-4032; RG7204; R7204; RO5185426; PLX4032
- 918504-65-1
Quick Details
- ProName: Vemurafenib
- CasNo: 918504-65-1
- Molecular Formula: C23H18ClF2N3O3S
- PackAge: 10mg;50mg;100mg
- ProductionCapacity: 50-100 Metric Ton/Day
- Purity: 98% min
- Storage: -20℃
- LimitNum: 0 Metric Ton
Superiority
Vemurafenib (PLX4032, RG7204; RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
IC50 value: 31 nM(B-RafV600E); 48 nM (c-Raf )[1]
Target: B-RafV600E
Target: PLX4032 inhibits B-RAFV600E, C-RAF, as well as wildtype B-RAF, with IC50 of 31 nM, 48 nM and 100 nM, respectively. PLX4032 also inhibits several non-RAF kinases, including ACK1, KHS1, and SRMS, with IC50 of 18 nM to 51 nM [1].
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Details
Vemurafenib (PLX4032, RG7204; RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
IC50 value: 31 nM(B-RafV600E); 48 nM (c-Raf )[1]
Target: B-RafV600E
Target: PLX4032 inhibits B-RAFV600E, C-RAF, as well as wildtype B-RAF, with IC50 of 31 nM, 48 nM and 100 nM, respectively. PLX4032 also inhibits several non-RAF kinases, including ACK1, KHS1, and SRMS, with IC50 of 18 nM to 51 nM [1].
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