- Product Details
Keywords
- ABT-199
- GDC-0199; ABT199; ABT 199; GDC0199; GDC 0199; Venetoclax
- 1257044-40-8
Quick Details
- ProName: ABT-199
- CasNo: 1257044-40-8
- Molecular Formula: C45H50ClN7O7S
- PackAge: 5mg;10mg;50mg;
- ProductionCapacity: 50-100 Metric Ton/Day
- Purity: 98% min
- Storage: -20℃
- LimitNum: 0 Metric Ton
Superiority
ABT-199 (GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1.
IC50 Value: <0.01 nM (Ki)
Target: Bcl-2 selective
ABT-199 is a potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, currently in clinical trials.
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Details
ABT-199 (GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1.
IC50 Value: <0.01 nM (Ki)
Target: Bcl-2 selective
ABT-199 is a potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, currently in clinical trials.
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