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Home > Products >  Sorafenib

Sorafenib CAS NO.284461-73-0

  • Min.Order: 5 Gram
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  • Product Details

Keywords

  • Sorafenib
  • Nexavar;Bay 43-9006
  • 284461-73-0

Quick Details

  • ProName: Sorafenib
  • CasNo: 284461-73-0
  • Molecular Formula: C21H16ClF3N4O3
  • Appearance: white powder
  • PackAge: 5g/10g/25g/50g or 25kg/drum
  • ProductionCapacity: 50-100 Metric Ton/Day
  • Purity: 98%
  • Storage: -20℃
  • LimitNum: 5 Gram

Superiority

Sorafenib

SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).


url:www.medchemexpress.cn/sorafenib.html

Details

Sorafenib

SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).


url:www.medchemexpress.cn/sorafenib.html

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