- Product Details
Keywords
- Sorafenib
- Nexavar;Bay 43-9006
- 284461-73-0
Quick Details
- ProName: Sorafenib
- CasNo: 284461-73-0
- Molecular Formula: C21H16ClF3N4O3
- Appearance: white powder
- PackAge: 5g/10g/25g/50g or 25kg/drum
- ProductionCapacity: 50-100 Metric Ton/Day
- Purity: 98%
- Storage: -20℃
- LimitNum: 5 Gram
Superiority
Sorafenib
SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).url:www.medchemexpress.cn/sorafenib.html
Details
Sorafenib
SorafenibSorafenib(BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro. IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1] Target: Raf-1 Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).url:www.medchemexpress.cn/sorafenib.html