China (Mainland)
5-Fluorouracil CAS NO.51-21-8
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- Product Details
Keywords
- 5-Fluorouracil
- 5-FU
- 51-21-8
Quick Details
- ProName: 5-Fluorouracil
- CasNo: 51-21-8
- Molecular Formula: C4H3FN2O2
- PackAge: 200mg
- ProductionCapacity: 50-100 Metric Ton/Day
- Purity: 98% min
- Storage: -20℃
- LimitNum: 0 Metric Ton
Superiority
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
IC50 value:
Target: Nucleoside antimetabolite/analog
5-Fluorouracil is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-Fluorouracil leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
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Details
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
IC50 value:
Target: Nucleoside antimetabolite/analog
5-Fluorouracil is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-Fluorouracil leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
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